Physics at the Biomolecular Interface: Review on Ariel Fernandez’s Book by Weishi Meng

Book Review by Weishi Meng (Reproduced with permission) “Physics at the Biomolecular Interface” is the latest book by Ariel Fernandez (阿列尔·费尔南德斯), the physical chemist and mathematician who developed the center manifold thermodynamics, unraveling the physical basis for the onset of life, and discovered the dehydron (脱水元), an idea that laid the foundation for the new field of epistructural biology. The hardcover is […]

“Biomolecular Interfaces: Interactions, Functions and Drug Design”, the Latest Book by Ariel Fernandez

A new book by Ariel Fernandez has made its appearance on April 21, 2015. It is entitled “Biomolecular Interfaces: Interactions, Functions and Drug Design“. The publication particulars are: Hardcover: 372 pages Publisher: Springer; 2015 edition (April 21, 2015) Language: English ISBN-10: 3319168495 ISBN-13: 978-3319168494 Author: Ariel Fernandez Author Companies: Ariel Fernandez Consultancy; AF Innovation Author […]

PROTEIN FOLDING PROBLEM: IT’S THE MATRIX!

Solving the protein folding problem from physical principles is surely a daunting task and perhaps the main open challenge of the post-genomic era. It entails identifying the folding pathways that enable the protein to find its native structure and predict the latter solely from the amino acid sequence of the protein. Progress in this area has been hampered by unproductive borderline-theological discussions on the modeling […]

BYE BYE DEBYE, BUT WE ARE IN THE COLD NOW

Debye’s theory of water dielectrics is truly remarkable, especially given that he had no knowledge of the nanoscale structure of water. His crucial assumption that water polarization aligns with the internal electrostatic field paved the way for major progress and magically simplified the electrostatic theory. Debye never meant his theory to apply in contexts where water […]