Ariel Fernandez May Have Created a WaterMap Precursor in 2007

Contributed by Weishi L. Meng, reproduced from Science Transparency.    Drug designers often implement molecular therapies to block malfunctioning proteins that are causing disease. They do so by creating small molecules that bind to the intended protein target when suitably delivered. The procedure has its risks as unintended targets (off-target proteins) may also be hit or […]

Physics at the Biomolecular Interface: Review on Ariel Fernandez’s Book by Weishi Meng

Book Review by Weishi Meng (Reproduced with permission) “Physics at the Biomolecular Interface” is the latest book by Ariel Fernandez (阿列尔·费尔南德斯), the physical chemist and mathematician who developed the center manifold thermodynamics, unraveling the physical basis for the onset of life, and discovered the dehydron (脱水元), an idea that laid the foundation for the new field of epistructural biology. The hardcover is […]

“Biomolecular Interfaces: Interactions, Functions and Drug Design”, the Latest Book by Ariel Fernandez

A new book by Ariel Fernandez has made its appearance on April 21, 2015. It is entitled “Biomolecular Interfaces: Interactions, Functions and Drug Design“. The publication particulars are: Hardcover: 372 pages Publisher: Springer; 2015 edition (April 21, 2015) Language: English ISBN-10: 3319168495 ISBN-13: 978-3319168494 Author: Ariel Fernandez Author Companies: Ariel Fernandez Consultancy; AF Innovation Author […]

Ariel Fernandez at the Center of a Biotechnological Transformation (Reproduced from Science Transparency)

Interview reproduced from Science Transparency. Ariel Fernandez (also styled as Ariel Fernandez Stigliano) is a physical chemist and mathematician and the former Karl F. Hasselmann Endowed Chair Professor of Bioengineering at Rice University. He got his Ph. D. in record time from Yale University under the guidance of Oktay Sinanoglu (who recently passed away according to Yale News). Completed in less than two […]

EVOLUTIONARY TECHNOLOGY: LISTEN TO DARWIN BUT DON’T FORGET KIMURA

MONUMENTAL as it surely is, Darwin’s opus does not contain a theory of evolution, at least in the scientific sense. It does not enable us to make verifiable predictions, the hallmark of validation for scientific theory. Many a-priori evolutionary outcomes could in principle result from within a scenario where selection pressure becomes operative. Darwin only explains the […]

HUMAN EVOLUTION: NO EASY FIX

DISCLAIMER: THIS POST BY ARIEL FERNANDEZ STIGLIANO IS REPRODUCED WITH PERMISSION FROM PROJECT SYNDICATE. HUMANS are undeniably complex, and proud of it. No case, we believe, needs to be made for our biological superiority. Our biological functions are exquisitely regulated and resilient to external variations, owing to complicated webs of interactions. Unlike other species, we seem to […]

BYE BYE DEBYE, BUT WE ARE IN THE COLD NOW

Debye’s theory of water dielectrics is truly remarkable, especially given that he had no knowledge of the nanoscale structure of water. His crucial assumption that water polarization aligns with the internal electrostatic field paved the way for major progress and magically simplified the electrostatic theory. Debye never meant his theory to apply in contexts where water […]